Let us define your health profileDraw your wheel of life and let us find the right path togetherStart Biological age self-assessment
01Glucose and insulin02Fat and cholesterol03Appetite and energy04Thyroid05Mitochondria and antioxidants06Digestion and gut07Vitamins and minerals08Folate and methylation cycle09Amino acids and glutathione10Cardiovascular system11Bone and connective tissue12Muscle and exercise13Hormonal balance14Neurotransmitters15Inflammation16Ageing and telomeres17Xenobiotics and alcohol18Drug response19Clinical geneticsThe backbone of metabolism01Glucose and insulin02Fat and cholesterol03Appetite and energy04Thyroid05Mitochondria and antioxidants06Digestion and gut07Vitamins and minerals08Folate and methylation cycle09Amino acids and glutathione10Cardiovascular system11Bone and connective tissue12Muscle and exercise13Hormonal balance14Neurotransmitters15Inflammation16Ageing and telomeres17Xenobiotics and alcohol18Drug response19Clinical genetics◆The backbone of metabolismTryptophan5-HTPSerotoninTyrosineL-DOPADopamineBreakdown productsTPH2rs4570625HTR2Ars6311COMTrs4680ANKK1rs1800497MAOArs6323BDNFrs6265Telomere lengthStress resistanceTERTrs2736100TERCrs12696304FOXO3rs2802292Folate (dietary)THF5,10-methylene-THF5-methyl-THFMethionineSAMeSAHHomocysteinePhosphatidylcholineSHMT1rs1979277MTHFD1rs2236225MTHFRrs1801133rs1801131MTRrs1805087MTRRrs1801394BHMTrs3733890PEMTrs7946CystathionineCysteineGlutathioneCBSrs234706GSTP1rs1695GSTM1Inflammatory responseCRP levelIL6rs1800795TNFrs1800629CRPrs1205AngiotensinogenAngiotensin IIBlood pressureL-arginineNitric oxideAGTrs699ACErs4343NOS3rs1799983SuperoxideHydrogen peroxideWaterSOD2rs4880CATrs1001179GPX1rs1050450NFE2L2rs6721961NQO1rs1800566CaffeineParaxanthineAlcoholAcetaldehydeAcetateCYP1A2rs762551ADH1Brs1229984ALDH2rs671Drug responseCYP2C19rs4244285CYP2C9rs1799853SLCO1B1rs4149056VKORC1rs9923231GlucoseInsulin secretionInsulin sensitivitySLC2A2rs5400GCKRrs1260326TCF7L2rs7903146MTNR1Brs10830963PPARGrs1801282TriglyceridesVLDLLDLHDLAPOA5rs662799LPLrs328APOErs429358rs7412PCSK9rs11591147CETPrs708272LeptinSatiety signalEnergy balanceLEPRrs1137101MC4Rrs17782313FTOrs9939609T4 (thyroxine)T3 (active hormone)DIO1rs2235544DIO2rs225014OestrogenHydroxy-oestrogensMethoxy-oestrogensCYP1B1rs1056836COMTrs4680LactoseGlucose + galactoseGlutenMicrobiotaLCTrs4988235FUT2rs601338HLA-DQrs2187668Vitamin D25(OH)DCellular responseVitamin B12IronCYP2R1rs10741657GCrs2282679VDRrs1544410rs731236TCN2rs1801198HFErs1800562Bone mineral densityType I collagenCOL1A1rs1800012Fast-twitch fibresMitochondrial biogenesisPower and enduranceACTN3rs1815739PPARGC1Ars8192678GlucoseGlucose-6-phosphateFructose-1,6-bisphosphateGlyceraldehyde-3-phosphatePyruvateLactateAcetyl-CoAFatty acids (β-oxidation)CitrateIsocitrate2-OxoglutarateSuccinyl-CoASuccinateFumarateMalateOxaloacetateNADHFADH₂Electron transport chainATPDNA repairBRCA1BRCA2MLH1

Cellavia · Interactive pathway map

Metabolic Atlas

Explore the map of your metabolism.

  • 19metabolic pathways
  • 67genes
  • 66variants
  • 7-step guided tour
  • Tap a gene to see what it does
  • Full screen on mobile
Home/Services/Metabolic Atlas

Cellavia Metabolic Atlas

Your genes on the pathway map

See at a glance where your genetic findings sit in your metabolism. The atlas is a simplified map of the 19 metabolic pathways in the report; you review your own results with your physician in the results consultation.

  • 19 pathways, one map
  • Search by gene or RSID
  • 7-step guided tour
  • Full screen and mobile-friendly

Pathways / Overview

67 genes · 66 variants · 19 pathways

01Glucose and insulin02Fat and cholesterol03Appetite and energy04Thyroid05Mitochondria and antioxidants06Digestion and gut07Vitamins and minerals08Folate and methylation cycle09Amino acids and glutathione10Cardiovascular system11Bone and connective tissue12Muscle and exercise13Hormonal balance14Neurotransmitters15Inflammation16Ageing and telomeres17Xenobiotics and alcohol18Drug response19Clinical geneticsThe backbone of metabolism01Glucose and insulin02Fat and cholesterol03Appetite and energy04Thyroid05Mitochondria and antioxidants06Digestion and gut07Vitamins and minerals08Folate and methylation cycle09Amino acids and glutathione10Cardiovascular system11Bone and connective tissue12Muscle and exercise13Hormonal balance14Neurotransmitters15Inflammation16Ageing and telomeres17Xenobiotics and alcohol18Drug response19Clinical genetics◆The backbone of metabolismTryptophan5-HTPSerotoninTyrosineL-DOPADopamineBreakdown productsTPH2rs4570625HTR2Ars6311COMTrs4680ANKK1rs1800497MAOArs6323BDNFrs6265Telomere lengthStress resistanceTERTrs2736100TERCrs12696304FOXO3rs2802292Folate (dietary)THF5,10-methylene-THF5-methyl-THFMethionineSAMeSAHHomocysteinePhosphatidylcholineSHMT1rs1979277MTHFD1rs2236225MTHFRrs1801133rs1801131MTRrs1805087MTRRrs1801394BHMTrs3733890PEMTrs7946CystathionineCysteineGlutathioneCBSrs234706GSTP1rs1695GSTM1Inflammatory responseCRP levelIL6rs1800795TNFrs1800629CRPrs1205AngiotensinogenAngiotensin IIBlood pressureL-arginineNitric oxideAGTrs699ACErs4343NOS3rs1799983SuperoxideHydrogen peroxideWaterSOD2rs4880CATrs1001179GPX1rs1050450NFE2L2rs6721961NQO1rs1800566CaffeineParaxanthineAlcoholAcetaldehydeAcetateCYP1A2rs762551ADH1Brs1229984ALDH2rs671Drug responseCYP2C19rs4244285CYP2C9rs1799853SLCO1B1rs4149056VKORC1rs9923231GlucoseInsulin secretionInsulin sensitivitySLC2A2rs5400GCKRrs1260326TCF7L2rs7903146MTNR1Brs10830963PPARGrs1801282TriglyceridesVLDLLDLHDLAPOA5rs662799LPLrs328APOErs429358rs7412PCSK9rs11591147CETPrs708272LeptinSatiety signalEnergy balanceLEPRrs1137101MC4Rrs17782313FTOrs9939609T4 (thyroxine)T3 (active hormone)DIO1rs2235544DIO2rs225014OestrogenHydroxy-oestrogensMethoxy-oestrogensCYP1B1rs1056836COMTrs4680LactoseGlucose + galactoseGlutenMicrobiotaLCTrs4988235FUT2rs601338HLA-DQrs2187668Vitamin D25(OH)DCellular responseVitamin B12IronCYP2R1rs10741657GCrs2282679VDRrs1544410rs731236TCN2rs1801198HFErs1800562Bone mineral densityType I collagenCOL1A1rs1800012Fast-twitch fibresMitochondrial biogenesisPower and enduranceACTN3rs1815739PPARGC1Ars8192678GlucoseGlucose-6-phosphateFructose-1,6-bisphosphateGlyceraldehyde-3-phosphatePyruvateLactateAcetyl-CoAFatty acids (β-oxidation)CitrateIsocitrate2-OxoglutarateSuccinyl-CoASuccinateFumarateMalateOxaloacetateNADHFADH₂Electron transport chainATPDNA repairBRCA1BRCA2MLH1
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Metabolic Atlas

Explore your body's chemistry map in 7 steps

Substance: nutrient, hormone or intermediateGene: the recipe for an enzymeGenetic variation (RSID)One substance turns into anotherEnzyme that drives the conversion

The map is for information only; the selection of genes and variants is illustrative and contains no personal results. Drag to move around, and after clicking on the map use the scroll wheel to zoom.

Sources

  1. Metabolic pathways: Nicholson DE. Metabolic Pathways, 22nd edition. International Union of Biochemistry and Molecular Biology (IUBMB) and Sigma-Aldrich, 2003. The map has been simplified and redrawn by Cellavia on the basis of this source; it is not a copy of the original poster.
  2. Enzyme numbers: IUBMB Enzyme Commission (EC) classification.
  3. Gene names and variant IDs (RSID): HGNC gene nomenclature and the NCBI dbSNP database.

The language of genetics

Single-letter differences, personal responses

DNA
The molecule that carries the information cells need to build and run themselves, written in the letters A, T, G and C.
SNP
A single-letter difference at a specific position in the DNA that can vary from person to person.
Allele
One of the letter forms that can occur at the same position – for example A or G.
Genotype
The combination of the two alleles you carry at a position – one inherited from your mother, one from your father.
SNP
  • AANot a carrierNo effect allele
  • AGHeterozygousOne copy
  • GGHomozygousTwo copies
For every variant, the report shows your genotype and how many copies of the effect allele you carry.

Review your own map with your physician

The findings in your GenoMetabolics report are reviewed on this atlas with your physician in the results consultation.

Frequently asked questions

What people ask

Does the atlas show my personal results?

No. The atlas on this page is for information only and contains no personal results. The findings in your own GenoMetabolics report are reviewed with your physician in the results consultation.

How do I use the atlas?

Start the guided tour or tap a pathway to zoom in. Tap a gene to see its function and the variants analysed; you can also search by gene name or RSID.

Which analysis is it linked to?

The atlas is a simplified map of the 19 metabolic pathways in the GenoMetabolics report. GenoNutra findings can also be reviewed on the relevant pathways.

Consultation

Begin Your Personal Longevity Journey

To decide on the right protocol for you, let us review your medical history, your cellular status and your health goals together with our specialist physicians. Contact our team to arrange your first consultation.